The increasing evidence presented on the role of microbes and notably bacteria in aiding the maturation of the human immune system can no longer be ignored. Once a baby is born, the various conditions he is subjected to will influence his mibrobiome and in turn, the strength and capabilities of his immune system. An unbalanced microbiome favors the persistence of a hypersensitive Th2-oriented immune response, favoring the development of atopy (allergies).

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It has been observed that the gut microbiome of atopic children is characterized by a reduced neonatal bifidobacteria to clostridia ratio, caused by augmented clostridia and reduced bifidobacteria colonization. If an unbalanced microbiome may favor the development of atopic diseases, probiotics may be helpful because of their capacity of balancing the gut microecology, restoring the normal intestinal permeability, improving immunological gut barrier function and rebalancing the production of pro-inflammatory cytokines leading to atopic disorders.

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This is the precise foundation on which Lactobacillus fermentum PCC® operates which has been proven in the various clinical investigations carried out.